transcription regulation

Objective To analyze the transcription activation and possible regulation mechanism of human X-box binding protein 1 ( XBP1) gene 5 ′ upstream DNA sequence in different cell lines.

目的分析人类转录因子X-盒结合蛋白1（X-box binding proteinⅠ，XBP1）基因启动子在不同细胞系中转录活性的差别，研究其转录调控机制。

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The level of histone acetylation is regulated by the histone acetyltransferase ( HATS) with the acetylation modification of core histone. This further control gene transcription and gene expression regulation which resulted in gene activation or silence.

组蛋白乙酰转移酶（HATs）通过对核心组蛋白进行乙酰化修饰来调节组蛋白的乙酰化水平，从而调控基因的转录，参与基因的表达，并由此介导基因的激活或沉默。

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The functions of these differentially expressed genes were involved in basic metabolism, gene transcription regulation, transporter, DNA repair and replication, autolysin and methylation.

这些基因主要包括基础代谢有关基因，转运子基因，转录调控有关的基因，DNA复制及修复，细菌自溶酶以及甲基化酶基因等。

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Prediction of Transcription Factor Binding Sites and Combinatorial Regulation of Eukaryotes

转录因子结合位点和组合调控模式的研究

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The genes with lower expression function in areas such as transcription regulation, vesicular transport, iron metabolism, signal transduction, and extracellular matrix organization and biogenesis.

而那些低表达的基因，功能涉及转录调节、小泡运输、铁代谢、信号转导，以及细胞外基质的组成和生物转化。

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Histone modifications plays an important role in transcriptional regulation. Histone modification enzymes, such as HATs, HDACs, HMTs control the chromatin structure and gene expression, thus participate in gene transcription regulation of specific sites.

组蛋白修饰在基因转录调控中占有重要地位，在组蛋白修饰酶HATs、HDACs、HMTs的共同作用下控制着染色质的结构和基因的表达，从而参与特定位点的基因转录调控。

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Mechanism of Transcription Regulation Mediated by Sp1 and Sp3

Sp1和Sp3介导的转录调控

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The ING gene family is one of the most conservative gene families. Its functions are associated with chromatin remodeling, gene transcription, cell-cycle regulation, cell proliferation and apoptosis.

ING基因最早是通过消减杂交寻找抑癌基因的方法得到的，这个基因家族在进化中十分保守，功能上与染色质结构的调节、基因转录、细胞周期调控、细胞增殖以及细胞凋亡有关。

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Role of transcription factors Sp1 and Sp3 in the expressional regulation of ezrin in esophageal carcinoma cells

转录因子Sp1和Sp3对食管癌细胞ezrin基因的表达调控作用

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Alternative splicing is known as one of the most important regulation processes in post transcription of eukaryotes.

选择性剪接是真核生物在后转录过程中最为重要的调控机制之一。

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This means that in the mutant the changes of the protein level during albinic stage might be related to gene regulation at the transcription level.

可能返白系在返白期间蛋白质水平的变化与转录水平的基因调控有关。

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